Search on: ALKALOIDS, SENECIO 
Descriptors Found: 1
Displaying: 1 .. 1  

 1 / 1 DeCS     
Descriptor English:   Pyrrolizidine Alkaloids 
Descriptor Spanish:   Alcaloides de Pirrolicidina 
Descriptor Portuguese:   Alcaloides de Pirrolizidina 
Synonyms English:   Alkaloids, Pyrrolizidine
Alkaloids, Senecio
Senecio Alkaloids  
Tree Number:   D03.132.716
D03.633.100.772
Definition English:   A group of ALKALOIDS, characterized by a nitrogen-containing necine, occurring mainly in plants of the BORAGINACEAE; COMPOSITAE; and LEGUMINOSAE plant families. They can be activated in the liver by hydrolysis of the ester and desaturation of the necine base to reactive electrophilic pyrrolic CYTOTOXINS. 
History Note English:   73(71) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications EC economics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UR urine  
Record Number:   12200 
Unique Identifier:   D011763 

Occurrence in VHL:
 

Similar:

 
DeCS CID-10 SciELO LILACS LIS